Research Tool

ACE-031 Reconstitution Calculator

A soluble activin receptor type-IIB fusion protein referenced in myostatin-pathway and muscle-research literature. This page works out concentration, volume per measured amount, syringe units and preparations per vial for a reconstituted ACE-031 preparation, plus the mass-to-molar conversions for its stated molecular weight. Everything runs in your browser; nothing is transmitted or stored.

Also referenced as: Ramatercept, ACE031

Myostatin-pathway inhibitor
For research and educational purposes only. This is a unit-conversion tool for laboratory reference. It is not medical advice, not a dosing recommendation, and not an instruction for human use.

Inputs

Results

Concentration
2.5 mg/mL (2,500 mcg/mL)
Per syringe unit
25 mcg per unit
Volume per preparation
0.1 mL
Syringe units to draw
10 units
Preparations per vial
20 preparations

Worked example: a 5 mg vial reconstituted with 2 mL of bacteriostatic water. Change any input to recalculate.

A unit-conversion reference for laboratory work. Not a dosing recommendation and not an instruction for human use.

The pre-filled example, step by step

The inputs above are the neutral reference preparation this site uses everywhere the calculator appears: a 5 mg vial, 2 mL of bacteriostatic water, and a 250 mcg target amount. They are not a property of ACE-031 and not an amount anyone should draw — they exist so the arithmetic is visible before you change anything.

  1. Concentration. 5 mg ÷ 2 mL = 2.5 mg/mL (2,500 mcg/mL), which for ACE-031 is approximately 0.03125 mM at its stated molecular weight.
  2. Per syringe unit. A U-100 syringe divides 1 mL into 100 units, so one unit holds 2,500 mcg ÷ 100 = 25 mcg.
  3. Volume for the 250 mcg target. 250 mcg ÷ 2,500 mcg/mL = 0.1 mL, or 10 units on that syringe.
  4. Preparations per vial. 5,000 mcg ÷ 250 mcg = 20 preparations.

Arithmetic on a laboratory preparation, shown as a unit-conversion reference. Not medical advice, not a dosing recommendation, not an instruction for human use. The full derivation, and why the diluent volume is a choice rather than a constant, is on the main reconstitution calculator.

Mass and molar equivalents for ACE-031

Derived from the molecular weight recorded on the ACE-031 entry: ~80 kDa (glycosylated ActRIIB-Fc homodimer) — the entry states this as an approximate figure, so the equivalents below are approximate too. Concentration in molar units is what an in-vitro protocol is usually specified in.

Mass to molar conversions for ACE-031 at its stated molecular weight.
QuantityMolar equivalent
1 mg of ACE-03112.5 nmol (0.0125 µmol)
1 mcg of ACE-0310.0125 nmol
A 1 mg/mL solution0.0125 mM (12.5 µM)

Molar amount = mass ÷ molecular weight. Figures are shown to four significant digits and are a unit conversion, not a measurement.

Reconstitution recorded for ACE-031

Supplied as a lyophilized biologic requiring reconstitution and cold-chain storage; handled like an antibody-type protein rather than a small peptide.

Quoted from the ACE-031 entry. Amounts reported in the research literature for this compound are documented on that entry, under the disclaimer they belong with — they are not reproduced next to a calculator. Read the full ACE-031 entry.

Handling questions for ACE-031

Why is ACE-031's large size relevant to research handling?

Because ACE-031 is a ~80 kDa glycosylated Fc-fusion protein rather than a sub-10 kDa peptide, it behaves like an antibody-type biologic: it has a long circulating half-life driven by Fc recycling and requires cold-chain handling. This distinguishes its stability and dosing-interval considerations sharply from small synthetic peptides.

Answers are published on the ACE-031 entry. Educational summaries of research-literature context, not medical advice.

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