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Metabolic & Mitochondrial — Category Hub

Compounds studied in fat-metabolism, energy-regulation and mitochondrial research — AOD-9604, HGH Fragment 176-191, MOTS-c, AICAR, 5-Amino-1MQ, SLU-PP-332 and Adipotide.

For research and educational purposes only. This page is not medical advice. No dosing or human-use instructions are provided.

What this category covers

This category spans two families that are frequently grouped together but are chemically unrelated.

Growth-hormone fragments — AOD-9604 and HGH Fragment 176-191 — are C-terminal fragments of human growth hormone studied specifically for lipolytic activity separated from the growth-promoting and glucose-affecting properties of the full hormone. That separation is the entire research premise of both compounds.

Mitochondrial and metabolic small molecules — MOTS-c, AICAR, 5-Amino-1MQ and SLU-PP-332 — act on cellular energy-regulation pathways. MOTS-c is a mitochondrial-derived peptide encoded in mitochondrial DNA rather than nuclear DNA, which makes it genuinely unusual. AICAR is an AMPK activator, 5-Amino-1MQ an NNMT inhibitor, and SLU-PP-332 an ERR agonist — three distinct entry points into the same broad question of how cells regulate energy expenditure, which is why they are collectively described in the literature as exercise mimetics.

Note that most compounds in this group are not peptides. AICAR is a nucleoside, 5-Amino-1MQ and SLU-PP-332 are small molecules. They appear here because they are studied alongside peptides in the same metabolic-research context, not because they share a chemical class.

Entries in this category

Every entry in this category in the PeptiDex library, with its compound class and a one-line research summary. Follow any entry for the full research overview, mechanism, reported research dosing, and studied effects.

AOD-9604Modified GH-fragment peptide — A modified fragment of human growth hormone studied in lipolysis research.5-Amino-1MQSmall-molecule NNMT inhibitor — A small-molecule inhibitor of NNMT studied in fat-metabolism and mitochondrial research.Vitamin B12 (Methylcobalamin)Essential vitamin (cofactor) — A water-soluble vitamin commonly referenced as an injectable in metabolic and energy research.MOTS-cMitochondrial-derived peptide — A mitochondrial-derived peptide studied in metabolic regulation and exercise research.SLU-PP-332Small-molecule ERR agonist (exercise mimetic) — An ERR (estrogen-related receptor) agonist and exercise-mimetic compound referenced in metabolic research.Adipotide (FTPP)Modified GH-fragment peptide — A pro-apoptotic peptidomimetic referenced in adipose-tissue and metabolic research literature.AICARAMPK activator (small molecule) — An AMP-activated protein kinase (AMPK) activator studied in exercise-mimetic and energy-metabolism research.HGH Fragment 176-191Modified GH-fragment peptide — A 16-amino-acid C-terminal fragment of human growth hormone studied in lipolysis-related research.

Relationship to the GLP-1 family

The GLP-1 family is also metabolic research, but it is catalogued separately because those compounds are incretin-receptor agonists acting on appetite and glucose regulation — a different mechanism from the direct lipolytic and mitochondrial pathways covered here. Researchers comparing across the two categories should be careful not to treat "metabolic" as a single mechanism.

See also

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