Research Tool

IGF-1 LR3 Reconstitution Calculator

A long-acting analog of insulin-like growth factor-1 studied in IGF-axis research. This page works out concentration, volume per measured amount, syringe units and preparations per vial for a reconstituted IGF-1 LR3 preparation, plus the mass-to-molar conversions for its stated molecular weight. Everything runs in your browser; plan entries stay in this browser, with optional device-local saving and calendar export.

Also referenced as: Long R3 IGF-1, LR3-IGF-1

IGF-1 analog (Long R3 IGF-1 variant)MW Approximately 9111 g/mol
For research and educational purposes only. This is a unit-conversion tool for laboratory reference. It is not medical advice, not a dosing recommendation, and not an instruction for human use.

01 / Vial & administration

Slide to select. Type for precision. Results update as you adjust. Slider ranges are input controls, not recommended amounts.

mg

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mL

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Drag to choose an amount, or enter an exact number above.

Final solution volume (optional)
mL

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02 / Calculated draw

Arithmetic from your entries. Confirm the product, concentration and syringe with your pharmacist or clinician before administration.

Concentration
Amount per administration
Volume per administration
U-100 syringe marking
Whole administrations per vial
Remainder per vial

Enter the vial, water and administration amounts to calculate.

Syringe capacity

Whole administrations exclude dead space, handling losses and expiry. A calculated quantity is not a guarantee of usable supply. No rounding to a nearby syringe mark is performed.

Protocol schedule

Schedule an existing prescribed or approved protocol. This tool cannot determine how often you can safely take a peptide. Frequency, dose, reconstitution, storage and discard instructions must come from the product label and your clinician or pharmacist.

03 / Timing

04 / Your calendar

Complete your calculation and timing to build a schedule.

Calculations stay in this browser. Saving is optional and device-local. Calendar export creates a file; import it into your calendar and configure reminders there. PeptiDex does not send notifications.

Date & timeAmountDrawVial

Measurement reference: FDA guidance on concentration, syringe size and mg/mL/unit conversion errors.

A separate worked example, step by step

This separate arithmetic example uses a 5 mg vial, 2 mL of bacteriostatic water, and a 250 mcg target amount. They are not a property of IGF-1 LR3 and not an amount anyone should draw — these figures only illustrate the arithmetic.

  1. Concentration. 5 mg ÷ 2 mL = 2.5 mg/mL (2,500 mcg/mL), which for IGF-1 LR3 is approximately 0.2744 mM at its stated molecular weight.
  2. Per syringe unit. A U-100 syringe divides 1 mL into 100 units, so one unit holds 2,500 mcg ÷ 100 = 25 mcg.
  3. Volume for the 250 mcg target. 250 mcg ÷ 2,500 mcg/mL = 0.1 mL, or 10 units on that syringe.
  4. Preparations per vial. 5,000 mcg ÷ 250 mcg = 20 preparations.

Arithmetic on a laboratory preparation, shown as a unit-conversion reference. Not medical advice, not a dosing recommendation, not an instruction for human use. The full derivation, and why the diluent volume is a choice rather than a constant, is on the main reconstitution calculator.

Mass and molar equivalents for IGF-1 LR3

Derived from the molecular weight recorded on the IGF-1 LR3 entry: Approximately 9111 g/mol — the entry states this as an approximate figure, so the equivalents below are approximate too. Concentration in molar units is what an in-vitro protocol is usually specified in.

Mass to molar conversions for IGF-1 LR3 at its stated molecular weight.
QuantityMolar equivalent
1 mg of IGF-1 LR3109.8 nmol (0.1098 µmol)
1 mcg of IGF-1 LR30.1098 nmol
A 1 mg/mL solution0.1098 mM (109.8 µM)

Molar amount = mass ÷ molecular weight. Figures are shown to four significant digits and are a unit conversion, not a measurement.

Reconstitution recorded for IGF-1 LR3

Lyophilized; typically reconstituted with bacteriostatic water or dilute acetic acid for research use

Quoted from the IGF-1 LR3 entry. Amounts reported in the research literature for this compound are documented on that entry, under the disclaimer they belong with — they are not reproduced next to a calculator. Read the full IGF-1 LR3 entry.

Handling questions for IGF-1 LR3

What is IGF-1 LR3?

IGF-1 LR3 (Long R3 IGF-1) is an 83-amino-acid analog of insulin-like growth factor-1 with an arginine substituted at position 3 and a 13-amino-acid N-terminal extension. It is an IGF-1 receptor agonist engineered for very low IGF-binding-protein affinity and greatly extended stability.

Why does IGF-1 LR3 have such an extended half-life?

The Arg3 substitution plus the N-terminal extension sharply lower its affinity for IGF-binding proteins while improving metabolic stability, so the peptide circulates far longer than native IGF-1. The research literature reports it is roughly three times more potent than native IGF-1.

Answers are published on the IGF-1 LR3 entry. Educational summaries of research-literature context, not medical advice.

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